Topiramate Treatment of Essential Tremor in a Patient with Cognitive Deficits
نویسندگان
چکیده
This case report demonstrates a satisfying response to topiramate in a 79-year-old patient with disabling essential tremor in whom propranolol as well as primidone had to be discontinued due to severe side effects. After 28 months of topiramate treatment, a clear decline in Mini Mental State Examination (MMSE) could be observed, stressing the use of care in prescribing topiramate in elderly patients.
منابع مشابه
Drug-induced cerebral glucose metabolism resembling Alzheimer’s Disease: a case study
BACKGROUND With aging of society the absolute number and the proportion of patients with cognitive deficits increase. Multiple disorders and diseases can foster cognitive impairment, e.g., Alzheimer's disease (AD), depressive disorder, or polypharmacy. CASE PRESENTATION A 74 year old man presented to the Old Age Psychiatry Service with cognitive deficits while being treated for recurrent depr...
متن کاملMassive Bilateral Choroidal Detachment Induced by Administration of Topiramate
Topiramate is a sulfa-derivative antiepileptic drug which is also used for other indications such as essential tremor. A 79-year-old male was admitted to our center due to acute bilateral painless decline of vision. One month before admission, he had experienced essential tremor and treatment with topiramate 50 mg/day and propranolol 40 mg/day. Best-corrected visual acuity was 20/800 OD and 20/...
متن کاملTopiramate Therapy: Night Eating Cure with Five Year Sustained Weight Loss in an Obese Patient with Type 2 Diabetes
Obesity is a leading cause of morbidity and mortality and it is essential to identify potentially treatable contributors. Night eating causes weight gain and obesity, predicts poor weight loss outcomes and is associated with poorer diabetes control as well as diabetes complications. We report the successful treatment of a 70 year old female with diabetes, fighting obesity for many years, compli...
متن کاملOpen-label adjunctive topiramate in the treatment of unstable bipolar disorder.
OBJECTIVE To assess open-label adjunctive topiramate in the treatment of outpatients with unstable bipolar disorder (BD). METHOD Outpatients with DSM-IV-defined BD (I or II) exhibiting mood instability were enrolled in this 16-week, open-label, multicentre study. Topiramate was added to existing mood stabilizers and other psychotropic treatments. The primary effectiveness measure was the Clin...
متن کاملReview of topiramate for the treatment of epilepsy in elderly patients
Individuals over 65 years of age experience the new onset of seizures at a prevalence rate of roughly twice that of younger adults. Differences in physiology, need of concomitant medications, and liability for cognitive deficits in this population, make the choice of anticonvulsant drugs especially important. This paper reviews topiramate (TPM), a treatment for many types of seizures, with the ...
متن کامل